Abstract Background Temporal lobe epilepsy (TLE) is a high prevalence neurological disorder. Surgery has emerged as a promising treatment. Objective The objective of this work is to compare the surgical results of anterior temporal lobectomy (ATL) versus selective amygdalohippocampectomy (SAH) in a cohort of 132 patients. Methods We performed a retrospective study of 146 patients operated for TLE from 2008 to 2019. Initially, 13 patients were excluded from the study due to insufficient medical record data or follow-up loss. One patient was excluded from the analysis of the results due to death in the first postoperative week. We used the ILAE scale to classify seizure control after surgery. In patients with left hippocampal sclerosis, SAH was performed and in right temporal lobe epilepsy, ATL was the approach of choice. Results The mean follow-up time after surgery was 57.2 months (12–137). In our data analysis, we found that the group of patients undergoing ATL had a higher prevalence of being completely seizure-free (ILAE I) (57.1% versus 31%) and a higher rate of satisfactory seizure control (88.6% versus 69.3%) p = 0,006, when compared with patients undergoing SAH. Conclusions The literature is still controversial about seizure control concerning the technique used due to the lack of a robust methodology. Our data analysis identified the superiority of ATL over SAH in seizure outcomes. ATL may be the best option for adequately controlling seizures with minimal additional morbidity in countries with a cost limitation for extended propaedeutics.

Resumo Antecedentes A epilepsia do lobo temporal (TLE) é uma desordem neurológica de alta prevalência. A cirurgia surgiu como um tratamento promissor. Objetivo O objetivo deste trabalho é comparar os resultados da lobectomia temporal anterior (ATL) versus amigdalohipocampectomia seletiva (SAH) em uma coorte de 132 pacientes. Métodos Realizamos um estudo retrospectivo de 146 pacientes operados por TLE de 2008 a 2019. Inicialmente, 13 pacientes foram excluídos por insuficiência de dados em prontuário ou perda de seguimento. Um paciente foi excluído da análise por óbito na primeira semana de pós-operatório. Usamos a escala ILAE para classificar o controle das crises após a cirurgia. Em pacientes com esclerose hipocampal à esquerda, foi realizada a SAH, e na epilepsia do lobo temporal à direita, a ATL foi a abordagem de escolha. Resultados O tempo médio de seguimento após a cirurgia foi de 57,2 meses (12–137). Em nossa avaliação, encontramos que o grupo de pacientes submetidos à ATL apresentou maior prevalência de ausência total de crises (ILAE I) (57,1% versus 31%) e maior taxa de controle satisfatório da epilepsia (88,6% versus 69,3%) p = 0,006, quando comparado ao grupo submetido à SAH. Resultados A literatura ainda é controversa em relação à redução das crises de acordo com a técnica utilizada devido a falta de uma metodologia robusta. Nosso estudo identificou superioridade da ATL sobre a SAH nos desfechos convulsivos. ATL pode ser a melhor opção para controlar adequadamente as convulsões com morbidade adicional mínima em países com limitação de custo para propedêutica estendida.

RESUMO INTRODUÇÃO: a síndrome de Angelman (SA) é caracterizada por retardo mental grave, distúrbio da fala e desordem convulsiva. Essa condição genética rara está associada a alterações do receptor GABA-A. Pacientes portadores de SA necessitam ser sedados durante a feitura de eletroencefalograma (EEG), indicado para fins diagnósticos ou controle evolutivo. A dexmedetomidina, cuja ação independe do receptor GABA, promove sono semelhante ao fisiológico e pode viabilizar a feitura desse exame em pacientes com SA. RELATO DE CASO: paciente feminina, 14 anos, portadora de SA, fez EEG sob sedação com dexmedetomidina. O procedimento transcorreu sem intercorrências e não foi registrada bradicardia ou depressão respiratória. O exame foi interpretado com sucesso e atividade epileptiforme não foi observada. CONCLUSÃO: a dexmedetomidina promoveu sedação satisfatória, foi bem tolerada e possibilitou a interpretação do EEG em paciente com SA e desordem convulsiva.

ABSTRACT INTRODUCTION: Angelman syndrome is characterized by severe mental retardation and speech and seizure disorders. This rare genetic condition is associated with changes in GABAA receptor. Patients with Angelman syndrome need to be sedated during an electroencephalogram ordered for diagnostic purposes or evolutionary control. Dexmedetomidine, whose action is independent of GABA receptor, promotes a sleep similar to physiological sleep and can facilitate the performing of this examination in patients with Angelman syndrome. CASE REPORT: Female patient, 14 years old, with Angelman syndrome; electroencephalogram done under sedation with dexmedetomidine. The procedure was uneventful and bradycardia or respiratory depression was not recorded. The examination was successfully interpreted and epileptiform activity was not observed. CONCLUSION: Dexmedetomidine promoted satisfactory sedation, was well tolerated and enabled the interpretation of the electroencephalogram in a patient with Angelman syndrome and seizure disorder.

Although “intellectual disability” has widely replaced the term “mental retardation”, the debate as to whether this entity should be conceptualized as a health condition or as a disability has intensified as the revision of the World Health Organization (WHO)’s International Classification of Diseases (ICD) advances. Defining intellectual disability as a health condition is central to retaining it in ICD, with significant implications for health policy and access to health services. This paper presents the consensus reached to date by the WHO ICD Working Group on the Classification of Intellectual Disabilities. Literature reviews were conducted and a mixed qualitative approach was followed in a series of meetings to produce consensus-based recommendations combining prior expert knowledge and available evidence. The Working Group proposes replacing mental retardation with intellectual developmental disorders, defined as “a group of developmental conditions characterized by significant impairment of cognitive functions, which are associated with limitations of learning, adaptive behaviour and skills”. The Working Group further advises that intellectual developmental disorders be incorporated in the larger grouping (parent category) of neurodevelopmental disorders, that current subcategories based on clinical severity (i.e., mild, moderate, severe, profound) be continued, and that problem behaviours be removed from the core classification structure of intellectual developmental disorders and instead described as associated features.

O paradigma da gestão democrática da escola, enquanto prin cípio Constitucional crítico, indo além da dimensão burocrática da ad ministração clássica, e também, enquanto ideologia neoliberal do Estado mínimo, é problematizado neste texto para analisarmos suas perspectivas na contemporaneidade. Este trabalho, de natureza qualitativa, busca o conteúdo latente da realidade (LÜDKE; ANDRÉ, 1986) e utiliza, a pes quisa bibliográfica como caminho para articular síntese e análise, a partir do estado da arte (MINAYO, 2000). Apresenta a apropriação e distorção do conceito de gestão democrática, realizado pelas políticas educacionais neoliberais (BASTOS, 1999; LÜCK, 2006; LIBÂNEO, 2003). A pesquisa focaliza a docência como um trabalho de gestão do ensino (GAUTHIER, 1999), capaz de contribuir para a construção de uma cultura democrática e de uma autonomia na escola.

The paradigm of democratic management of the school, as a critical Constitutional principle, going beyond the classic bureaucratic administration, as well as the neoliberal ideology of Minimal State, is problematized in this paper to analyze their prospects nowadays. This study was qualitative, seeking the latent content of reality (LÜDKE; ANDRÉ, 1986) and uses bibliographic research as a way to articulate the synthesis and analysis from the state of the art (MINAYO, 2000). It presents the appropriation and distortion of the concept of democratic management, carried out by neo-liberal educational policies (Bastos, 1999; LÜCK, 2006; LIBÂNEO, 2003). The research focuses on teaching pratice as a teaching management work (Gauthier, 1999), able to contribute to building of a democratic culture and autonomy in school.

Purpose: The current study provides a comprehensive analysis of the content of advertisements on Websites targeted at adolescents, with a particular focus on the female beauty ideal. Methods: Advertisements (N_631) from 14 Websites popular with adolescents were analyzed with respect to product advertised, characteristics of people presented, and emphasis on appearance and the thin beauty ideal. Results: Although a wide variety of products were featured, advertisements for cosmetics and beauty products were the most frequent. Further, many of the products advertised (e.g., dating services, weight loss products, gambling games) might be considered inappropriate for the intended audience (i.e., teenagers) of the Web site. People who were a part of advertisements were generally female, young, thin, and attractive. Advertisements for games, weight loss products, and cosmetic and beauty products strongly focused on appearance and laid emphasis on the thin ideal. Conclusions: Like advertisements in mainstream media, advertising on the Internet perpetuates the stereotypical ideal of feminine beauty. Adolescents using the Internet are likely to be exposed to numerous advertisements that reinforce the importance of beauty and thinness, which could have a detrimental impact on how they feel about their bodies

O presente trabalho avaliou o efeito da adubação orgânica na produção total de batata-doce, por meio de um experimento realizado no período de julho a novembro de 2007, na Estação Experimental de Lagoa Seca, PB, Brasil. O delineamento experimental foi em blocos casualizados com cinco tratamentos (0, 3, 6, 9 e 12 t ha-1 de cama-de-aviário), em quatro repetições. A parcela foi composta por quatro leiras de 3,6 m de comprimento, espaçados de 0,80 m entre leiras e de 0,30 m entre plantas, sendo colhidas as duas fileiras centrais. As variáveis estudadas foram: produção total, raízes de tamanho graúdas e miúdas de batata-doce. A produção de raízes graúdas, miúdas e total por planta (14,20; 3,84 e 18,03 t ha-1) de batata-doce responderam de forma linear e positiva às doses crescentes de cama-de-aviário. A adubação com cama-de-aviário aumentou a produção de raízes graúdas, miúdas e total de batata-doce.

The present study evaluated the effect of organic fertilization in the total production of sweet potato. The experiment was performed in the period between July and November 2007, at the Lagoa Seca Experimental Station, Paraíba, Brazil. The experimental design was randomized blocks with five treatments (0, 3, 6, 9 and 12 t ha-1), in four replications. The plot consisted of four 3.6 m long ridges, spaced of 0.80 m between ridges and 0.30 m between plants; the two central ridges were harvested. The variables studied were: total yield, large and small sweet potato roots. The production of large and small roots, total yield per plant (14.20, 3.84 and 18.03 t ha-1) of sweet potato, responded positively in a linear fashion to increasing doses of poultry litter. The fertilization with poultry litter increased the yield of large, small and total roots of sweet potato.